TruaceTracing the truth around AIMonday, September 14, 2026

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A machine learning-derived sarcopenia index is associated with survival and nonrelapse mortality in DLBCL
HealthContested · G 74 / P 72

machine learning-derived CT body composition assessment of sarcopenia and survival outcomes in DLBCL patients receiving immunochemotherapy

Source article: A machine learning-derived sarcopenia index is associated with survival and nonrelapse mortality in DLBCL

Problem

In DLBCL patients treated with first-line immunochemotherapy, CT-measured sarcopenia in the lowest tertile of muscle mass is associated with inferior overall survival driven by nonrelapse mortality and higher risk of hematologic toxicity.

Blood Advances
Gain

Machine learning-supported body composition analysis applied to CT imaging quantifies radiologic sarcopenia and enables risk stratification for survival after first-line immunochemotherapy in newly diagnosed DLBCL.

Blood Advances
Advancing hirschsprung disease diagnosis: a systematic review of the development and application of artificial intelligence in histopathological analysis
HealthPositive state · G 77 / P 72

AI-assisted histopathological diagnosis of Hirschsprung disease

Source article: Advancing hirschsprung disease diagnosis: a systematic review of the development and application of artificial intelligence in histopathological analysis

Problem

69% of studies showed high risk of bias from small sample sizes, patch-level data partitioning, and no external test sets, raising concerns about overfitting and data leakage.

Pediatric Surgery International
Gain

Deep learning models for Hirschsprung disease histopathology achieved over 90% ganglion cell detection and cut diagnostic time by 50-95%, increasing accuracy and accelerating clinical decision-making.

Pediatric Surgery International
Mapping agricultural fragility in India through a yield gap vulnerability framework: a national-scale machine learning assessment
CrimeContested · G 69 / P 72

district-level agricultural vulnerability to yield gaps in India assessed by ML-based YGV framework

Source article: Mapping agricultural fragility in India through a yield gap vulnerability framework: a national-scale machine learning assessment

Problem

Despite increased modal yields for rice and wheat, regional yield gaps continue to widen and the share of high-vulnerability districts has risen, particularly in resource-stressed regions such as the Indo-Gangetic Plains, driven by socioeconomic inequality and climate variability.

Journal of Environmental Management
Gain

The integrated ML-based Yield Gap Vulnerability framework provides a data-driven decision-support tool that can support sustainable agricultural management, spatial planning and risk reduction by identifying vulnerability hotspots for region-specific measures in India.

Journal of Environmental Management
The Role of Artificial Intelligence Models in Predicting Post-Prosthetic Facial Esthetics in Edentulous Patients: Clinical and Anthropometric Comparative Study
HealthContested · G 70 / P 66

AI prediction of post-denture facial esthetics in edentulous patients

Source article: The Role of Artificial Intelligence Models in Predicting Post-Prosthetic Facial Esthetics in Edentulous Patients: Clinical and Anthropometric Comparative Study

Problem

AI simulations failed to accurately reproduce quantitative facial anthropometric changes after denture placement despite visual similarity.

European Journal of Dentistry
Gain

AI models Gemini and FaceApp generated post-denture facial images rated as esthetically comparable to actual clinical outcomes by patients and experts.

European Journal of Dentistry
Automated artificial intelligence performance for longitudinal pulmonary nodule matching in lung cancer screening
HealthContested · G 67 / P 70

automated longitudinal matching of persisting pulmonary nodules >=100 mm3 in UKLS 3-month follow-up LDCT

Source article: Automated artificial intelligence performance for longitudinal pulmonary nodule matching in lung cancer screening

Problem

Automated matching failed for 16.5% of persisting findings and performance fell to 72.8% in participants with more than five nodules, with prospective validation in diverse populations still needed.

European Radiology
Gain

Automated pulmonary AI matched persisting lung nodules across 3-month LDCT scans with 83.5% success, reaching 91.8% for single-nodule cases and leaving only 1.5% of persisting findings needing manual correction, indicating potential to reduce manual tracking workload.

European Radiology
Machine learning for monitoring and assessment of potentially toxic elements in soils: a synthesis of spatial validation, explainability, and uncertainty
ClimateContested · G 69 / P 72

machine learning mapping of potentially toxic elements in soils for monitoring and risk assessment

Source article: Machine learning for monitoring and assessment of potentially toxic elements in soils: a synthesis of spatial validation, explainability, and uncertainty

Problem

Many ML studies of soil potentially toxic elements rely on spatially naive validation, and random cross-validation often overestimates predictive performance when spatial dependence is ignored, with incomplete uncertainty reporting.

Environmental Monitoring and Assessment
Gain

Machine learning can map potentially toxic element concentrations from environmental covariates and produce exceedance-probability maps aligned with regulatory thresholds for soil-contamination management.

Environmental Monitoring and Assessment
Clinical phenotyping of bloodstream infections: a review of current evidence
HealthContested · G 70 / P 66

data-driven clinical subphenotyping of bloodstream infections to stratify mortality risk and guide therapy

Source article: Clinical phenotyping of bloodstream infections: a review of current evidence

Problem

Studies use inconsistent phenotyping methods and provide limited validation, slowing translation of AI-derived BSI subphenotypes into routine clinical practice.

Clinical Microbiology and Infection
Gain

Unsupervised machine learning applied to bloodstream infections identifies reproducible clinical subphenotypes with different mortality, supporting bedside tools for rapid phenotype assignment and personalized antimicrobial therapy.

Clinical Microbiology and Infection
Association between body composition and recurrence in stage II-III colon cancer: a retrospective cohort study
HealthContested · G 70 / P 67

machine-learning-derived myosteatosis as predictor of recurrence in stage II-III colon cancer

Source article: Association between body composition and recurrence in stage II-III colon cancer: a retrospective cohort study

Problem

Patients with stage II-III colon cancer whose CT body composition showed myosteatosis via machine learning analysis had significantly lower 5-year recurrence-free survival.

Clinical Nutrition ESPEN
Gain

Using a machine learning model to measure CT body composition at L3 identified myosteatosis as an independent predictor of recurrence in stage II-III colon cancer.

Clinical Nutrition ESPEN
Reinventing the echocardiography workflow: from manual quantification to artificial intelligence-driven comprehensive interpretation
HealthContested · G 72 / P 74

AI-driven echocardiography workflow and its effects on examination performance and clinical implementation

Source article: Reinventing the echocardiography workflow: from manual quantification to artificial intelligence-driven comprehensive interpretation

Problem

Clinical use of AI in echocardiography carries risk of automation bias in high-volume settings, compounded by inconsistent performance across platforms.

Journal of Cardiovascular Imaging
Gain

AI integration in echocardiography workflows reduces examination time and automates measurements, enabling more comprehensive data collection while reducing sonographer fatigue.

Journal of Cardiovascular Imaging
Naïve adaptive immune receptor repertoires in celiac disease assessed by machine learning; impact of the HLA-DQ2.5 allotype on the TCR repertoire
HealthContested · G 68 / P 68

machine-learning classification of celiac disease status from naive adaptive immune receptor repertoires

Source article: Naïve adaptive immune receptor repertoires in celiac disease assessed by machine learning; impact of the HLA-DQ2.5 allotype on the TCR repertoire

Problem

After accounting for HLA-DQ2.5 enrichment, machine-learning classification of celiac disease from naive TCR repertoires was abolished, and naive BCR repertoires failed to classify disease.

Immunogenetics
Gain

Naive CD4+ TCR repertoire features enabled moderate machine-learning classification of celiac disease status and high-accuracy prediction of HLA-DQ2.5 status by publication date.

Immunogenetics
International Application of Artificial Intelligence for Lesion Detection on Digital Breast Tomosynthesis: Comparing Western and Eastern Databases
HealthContested · G 71 / P 71

AI lesion detection on digital breast tomosynthesis across Western and Eastern databases

Source article: International Application of Artificial Intelligence for Lesion Detection on Digital Breast Tomosynthesis: Comparing Western and Eastern Databases

Problem

AI lesion detection models trained on Western or Eastern DBT data showed reduced performance when applied to the other population due to differences in lesion types.

Academic Radiology
Gain

Transfer learning enhanced AI lesion detection performance when models were adapted from one regional DBT database to another.

Academic Radiology
Predicting Synchronous Liver Metastasis in Pancreatic Cancer Using CT Radiomics and Clinical Features: A Machine Learning Approach
HealthContested · G 72 / P 70

machine learning prediction of synchronous liver metastasis in pancreatic cancer using CT radiomics and clinical features

Source article: Predicting Synchronous Liver Metastasis in Pancreatic Cancer Using CT Radiomics and Clinical Features: A Machine Learning Approach

Problem

The linear LDA model showed unstable performance and poor discrimination in lymph-node-negative and pancreatic head tumor subgroups despite overall validation AUC.

Academic Radiology
Gain

Integrated machine learning models using CT radiomics and clinical predictors achieved accurate preoperative prediction of synchronous liver metastasis in pancreatic ductal adenocarcinoma in validation, intended to assist decisions on surveillance versus biopsy or neoadjuvant therapy for indeterminate subcentimeter CT-

Academic Radiology
Attitudes, perceptions, and UTAUT-based factors influencing the acceptance of medical artificial intelligence among Chinese oncology healthcare professionals: a national cross-sectional survey
HealthNegative state · G 65 / P 70

adoption and use of medical AI among Chinese oncology healthcare professionals

Source article: Attitudes, perceptions, and UTAUT-based factors influencing the acceptance of medical artificial intelligence among Chinese oncology healthcare professionals: a national cross-sectional survey

Problem

Despite high awareness, most Chinese oncology professionals have not practically integrated medical AI, with only 17.7% reporting both hearing of and using it and 67.7% hearing but never using it.

JAMIA Open
Gain

Among Chinese oncology professionals, higher trust in system reliability and higher effort expectancy were associated with stronger behavioral intention to adopt medical AI.

JAMIA Open
Deep Learning for Synthetic Postcontrast T1-Weighted MRI: A Systematic Review With Targeted Meta-Analysis of Brain Tumor Studies
HealthNegative state · G 66 / P 73

deep learning synthesis of postcontrast T1-weighted MRI from precontrast sequences for brain tumor imaging

Source article: Deep Learning for Synthetic Postcontrast T1-Weighted MRI: A Systematic Review With Targeted Meta-Analysis of Brain Tumor Studies

Problem

Clinical translation is limited by inconsistent evaluation, substantially lower performance on pathology-specific regions, and reliance on single-institution data with few reader studies or external validation.

American Journal of Roentgenology
Gain

Systematic review and meta-analysis of 15 brain tumor studies found deep learning synthesis of postcontrast T1-weighted MRI from precontrast sequences alone is technically feasible with high whole-image similarity.

American Journal of Roentgenology
Robotic Ultrasound Imaging: A Comprehensive Review of Historical Evolution, Current State-of-the-Art, and Future Perspectives
HealthContested · G 70 / P 70

reproducibility and global accessibility of ultrasound imaging

Source article: Robotic Ultrasound Imaging: A Comprehensive Review of Historical Evolution, Current State-of-the-Art, and Future Perspectives

Problem

Conventional ultrasound imaging's profound reliance on operator expertise restricts reproducibility and global accessibility.

Journal of Ultrasound in Medicine
Gain

Robotic ultrasound systems improve reproducibility and global accessibility by decoupling the operator from the patient and using 5G telesonography to project diagnostic expertise.

Journal of Ultrasound in Medicine