Health

All Diagnostics & Imaging Drug Discovery Mental Health Hospitals & Care

454 stories · page 24 of 31

Evidence-backed problem

Artificial intelligence and radiologists in prostate cancer detection on MRI (PI-CAI): an international, paired, non-inferiority, confirmatory study

BACKGROUND: Artificial intelligence (AI) systems can potentially aid the diagnostic pathway of prostate cancer by alleviating the increasing workload, preventing overdiagnosis, and reducing the dependence on experienced radiologists. We aimed to investigate the performance of AI systems at detecting clinically significant prostate cancer on MRI in comparison with radiologists using the Prostate Imaging-Reporting and Data System version 2.1 (PI-RADS 2.1) and the standard of care in multidisciplinary routine pract…

The Lancet Oncology · Health

Evidence-backed gain

A Survey on Medical Large Language Models: Technology, Application, Trustworthiness, and Future Directions

With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve patient outcomes. Considering this rapid technical progress, in this survey, we trace the recent advances of Medical Large Language Models (Med-LLMs), including the background, key findings, and mainstream techniques, especially for the evolution from general-purpose models to…

Health

Both readings

User perceptions and experiences of an AI-driven conversational agent for mental health support

Background: The increasing prevalence of artificial intelligence (AI)-driven mental health conversational agents necessitates a comprehensive understanding of user engagement and user perceptions of this technology. This study aims to fill the existing knowledge gap by focusing on Wysa, a commercially available mobile conversational agent designed to provide personalized mental health support. Methods: A total of 159 user reviews posted between January, 2020 and March, 2024, on the Wysa app's Google Play page we…

Health

Evidence-backed gain

A foundation model for clinical-grade computational pathology and rare cancers detection

The analysis of histopathology images with artificial intelligence aims to enable clinical decision support systems and precision medicine. The success of such applications depends on the ability to model the diverse patterns observed in pathology images. To this end, we present Virchow, the largest foundation model for computational pathology to date. In addition to the evaluation of biomarker prediction and cell identification, we demonstrate that a large foundation model enables pan-cancer detection, achievin…

Health

Both readings

Large Language Models for Wearable Sensor-Based Human Activity Recognition, Health Monitoring, and Behavioral Modeling: A Survey of Early Trends, Datasets, and Challenges

The proliferation of wearable technology enables the generation of vast amounts of sensor data, offering significant opportunities for advancements in health monitoring, activity recognition, and personalized medicine. However, the complexity and volume of these data present substantial challenges in data modeling and analysis, which have been addressed with approaches spanning time series modeling to deep learning techniques. The latest frontier in this domain is the adoption of large language models (LLMs), su…

Health

Both readings

Recent Advances in Microfluidic Chip Technology for Laboratory Medicine: Innovations and Artificial Intelligence Integration

Microfluidic chip technologies, also known as lab-on-a-chip systems, have profoundly transformed laboratory medicine by enabling the miniaturization, automation, and rapid processing of complex diagnostic assays using minimal sample volumes. Recent advances in chip design, fabrication methods-including 3D printing, modular and flexible substrates-and biosensor integration have significantly enhanced the performance, sensitivity, and clinical applicability of these devices. Integration of advanced biosensors allo…

Health

Both readings

Human in the loop artificial intelligence in healthcare: applications, outcomes, and implementation challenges

BACKGROUND: The integration of artificial intelligence in healthcare has transformed clinical practice and research methodologies. However, concerns regarding algorithmic accountability, interpretability, and safety have necessitated human oversight in AI systems. Human in the loop artificial intelligence represents a collaborative paradigm where human expertise and machine intelligence converge to enhance decision making while maintaining ethical standards and clinical safety. AIM: This review synthesizes curre…

Health

The AI-IARA framework: How to cultivate human agency before artificial intelligence optimizes it a(ny)way

We are the last generation that will influence what wellbeing means before AI systems optimize that definition for us. While AI promises unprecedented scalability in mental health support, emerging evidence reveals a troubling pattern: the systems designed to enhance human flourishing may systematically erode the capacities required to achieve. This paper introduces the AI-IARA framework, identifying six irreducible human capacities essential for wellbeing under algorithmic conditions: Awareness (the ability to…

Health

Hallucinating with AI: Distributed Delusions and “AI Psychosis”

Abstract There is much discussion of the false outputs that generative AI systems such as ChatGPT, Claude, Gemini, DeepSeek, and Grok create. In popular terminology, these have been dubbed “AI hallucinations”. However, deeming these AI outputs “hallucinations” is controversial, with many claiming this is a metaphorical misnomer. Nevertheless, in this paper, I argue that when viewed through the lens of distributed cognition theory, we can better see the dynamic ways in which inaccurate beliefs, distorted memories…

Health

Hallucinating with AI: Distributed Delusions and “AI Psychosis”

Multimodal Large Language Models in Health Care: Applications, Challenges, and Future Outlook

In the complex and multidimensional field of medicine, multimodal data are prevalent and crucial for informed clinical decisions. Multimodal data span a broad spectrum of data types, including medical images (eg, MRI and CT scans), time-series data (eg, sensor data from wearable devices and electronic health records), audio recordings (eg, heart and respiratory sounds and patient interviews), text (eg, clinical notes and research articles), videos (eg, surgical procedures), and omics data (eg, genomics and prote…

Health

The EU Artificial Intelligence Act (2024): Implications for healthcare

• The EU Artificial Intelligence Act entered into force in August 2024. • The Artificial Intelligence Act stipulates new rules for the healthcare sector. • This paper highlights the new obligations of technology developers and health professionals. • The Artificial Intelligence Act insufficiently addresses the interests of patients. • Sector-specific guidelines are necessary in the healthcare sector. In August 2024, the EU Artificial Intelligence Act (AI Act) entered into force. This legally binding instrument s…

Health

Artificial Intelligence-Driven Development and Characterization of Nanomedicine

Abstract Nanomedicine has enabled major advances in targeted therapeutics by improving drug bioavailability, precision delivery, and safety profiles. However, the rational design and reproducible synthesis of nanoparticles with tightly controlled physicochemical attributes such as size, morphology, and surface characteristics remain significant challenges due to the complex, nonlinear interplay of formulation and process parameters. Artificial intelligence (AI) and machine learning (ML) have emerged as powerful…

Health

A framework for human evaluation of large language models in healthcare derived from literature review

With generative artificial intelligence (GenAI), particularly large language models (LLMs), continuing to make inroads in healthcare, assessing LLMs with human evaluations is essential to assuring safety and effectiveness. This study reviews existing literature on human evaluation methodologies for LLMs in healthcare across various medical specialties and addresses factors such as evaluation dimensions, sample types and sizes, selection, and recruitment of evaluators, frameworks and metrics, evaluation process,…

Health

“It happened to be the perfect thing”: experiences of generative AI chatbots for mental health

The global mental health crisis underscores the need for accessible, effective interventions. Chatbots based on generative artificial intelligence (AI), like ChatGPT, are emerging as novel solutions, but research on real-life usage is limited. We interviewed nineteen individuals about their experiences using generative AI chatbots for mental health. Participants reported high engagement and positive impacts, including better relationships and healing from trauma and loss. We developed four themes: (1) a sense of…

Health

Revolutionizing healthcare and medicine: The impact of modern technologies for a healthier future—A comprehensive review

The increasing integration of new technologies is driving a fundamental revolution in the healthcare sector. Developments in artificial intelligence (AI), machine learning, and big data analytics have completely transformed the diagnosis, treatment, and care of patients. AI-powered solutions are enhancing the efficiency and accuracy of healthcare delivery by demonstrating exceptional skills in personalized medicine, early disease detection, and predictive analytics. Furthermore, telemedicine and remote patient m…

Health